Plasma Creatinine

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Calculation of creatinine clearance from plasma creatinine.

Glomerular filtration rate (GFR) is commonly assessed by measurement of endogenous creatinine clearance (Ccr). Several formulae have been described to calculate Ccr from plasma creatinine. I have evaluated the effectiveness of four formulae in 35 healthy subjects (21M and 14F, 18-34 years) and in 41 patients (24M, 17F, 20-69 years) attending a renal clinic with diminished renal function (serum ...

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The assessment of glomerular function: creatinine clearance or plasma creatinine?

Plasma creatinine concentration is superior to creatinine clearance for the detection of abnormal glomerular function, of changes of glomerular function in patients with chronic renal disease. Creatinine clearance should be abandoned as the routine assessment of glomerular function.

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Simple estimate of creatinine clearance from plasma creatinine in neonates.

Thirteen newborn infants, 8 preterm and 5 term, with either mild or serious neonatal asphyxia were studied. From the first 24 hours of life to day 13, glomerular filtration rate (GFR) estimated by creatinine clearance was compared with the values obtained using Schwartz's formula: GFR (ml/min per 1.73 m2) = 0.55 x length (cm)/plasma creatinine (mg/100 ml). Both in term and preterm infants, valu...

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Relation between plasma creatinine and body size.

We studied the relationship between creatinine concentration in plasma and body size in 673 healthy individuals (385 women, 288 men). Weight, height, and skinfold thickness were measured and blood was sampled (after a short fast) for estimations of urea and creatinine in plasma. Lean body mass was calculated according to Durnin and Wormsley (Br J Nutr 1974; 32:77-97). Concentrations of urea and...

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Plasma chromogen and the endogenous creatinine clearance.

One of the troubles of using the endogenous creatinine clearance to measure the filtration rate is that plasma and serum contain chromogens, other than creatinine, which give a colour with the Jaffe reaction. The creatinine can, however, be isolated by adsorption on Fuller's earth (Gaebler and Keltch, 1928) and subsequently eluted with the alkaline picrate used for colour production (Borsook, 1...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1955

ISSN: 0021-9746

DOI: 10.1136/jcp.8.2.160